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EXUS as partner

Validation and Comparitive Multi-Omics Benchmarking of Fluid-Derived Volatilomics Biomarkers for the
Prevention and Early detection of Schizophrenia

Early Detection of Schizophrenia Through Science and Innovation: Schizophrenia remains one of the most complex and challenging mental health conditions to diagnose early and accurately. Traditional methods often result in late detection and misdiagnosis, delaying access to proper treatment and support. VOLABIOS addresses this gap by introducing a revolutionary, non-invasive approach to early schizophrenia (SZ) detection. VOLABIOS project brings together advanced portable spectrometry, multi-omics analysis, and VOC biomarker validation to create a comprehensive diagnostic framework. By focusing on early-stage identification — even before symptoms fully emerge — VOLABIOS enables faster diagnosis, reduces clinical uncertainty, and supports better patient outcomes. Using real-time Ion Mass Spectrometry (IMS) and innovative digital tools, VOLABIOS delivers accessible, low-cost diagnostic solutions that are validated through extensive clinical studies involving over 3,600 participants across Europe. At its core, the project combines cutting-edge science with co-design and citizen engagement to ensure its tools are practical, ethical, and ready for real-world healthcare systems. VOLABIOS is not just about technology — it’s about transforming mental healthcare, starting with how we detect and understand schizophrenia.

Numbers

1/1/2025-30/6/2029

Project duration

7,988,082.73

Overall Budget

HORIZON-HLTH-2024-DISEASE-03-13-two-stage

Topic

Impact

VOLABIOS has the potential to fundamentally transform the early detection and management of schizophrenia (SZ), addressing a longstanding diagnostic bottleneck in psychiatric care. By integrating real-time Ion Mass Spectrometry (IMS), multi-omics profiling, and validated VOC biomarkers, the project delivers a novel, non-invasive diagnostic framework capable of identifying SZ at its earliest stages — potentially even before clinical symptoms manifest. This paradigm shift enables timely intervention, reduces misdiagnosis, and improves long-term patient outcomes.

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY (TECH)
EXUS SOFTWARE MONOPROSOPI ETAIRIA PERIORISMENIS EVTHINIS (EXUS)
SERVICIO ANDALUZ DE SALUD (SAS)
UNIVERSITAETSKLINIKUM AACHEN (UKA)
LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS (LSMU)
FIRALIS (Firalis)

Partners

UNIVERSIDADE DE COIMBRA (UC)
HEINRICH-HEINE-UNIVERSITAET DUESSELDORF (UDUS)
SMART NANO SENSE LTD (SNSI)
ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS (CERTH)
AINIGMA TECHNOLOGIES (AINIGMA)
YPOURGEIO YGEIAS (MoHGR)

UNIVERSIDAD DE LA RIOJA (UNIRIOJA)
TIMELEX (TLX)
GESELLSCHAFT ZUR FORDERUNG EMPIRISCH BEGRUNDETER
CUBIC SNAIL O.P. (CUBIC)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE (UCAM)
ZENTRUM FUR SOZIALE INNOVATION GMBH (ZSI)

Partners

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